High Glucose Suppresses Keratinocyte Migration Through the Inhibition of p38 MAPK/Autophagy Pathway

Wound healing is delayed frequently in patients with diabetes. Proper keratinocyte migration is an essential step during re-epithelialization. Impaired keratinocyte migration is a critical underlying factor responsible for the deficiency of diabetic wound healing, which is mainly attributed to the h...

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Bibliographic Details
Main Authors: Lingfei Li, Junhui Zhang, Qiong Zhang, Dongxia Zhang, Fei Xiang, Jiezhi Jia, Ping Wei, Jiaping Zhang, Jiongyu Hu, Yuesheng Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00024/full