A phase 4 multicentre, 2×2 factorial randomised, double-blind, placebo-controlled trial to investigate the efficacy and safety of tobramycin inhalation solution for Pseudomonas aeruginosa eradication in bronchiectasis: ERASE

A phase 4 multicentre, 2×2 factorial randomised, double-blind, placebo-controlled trial to investigate the efficacy and safety of tobramycin inhalation solution for Pseudomonas aeruginosa eradication in bronchiectasis: ERASE

Chronic Pseudomonas aeruginosa (PA) infection significantly contributes to morbidity and mortality in bronchiectasis patients. Initiating antibiotics early may lead to the eradication of PA. Here we outline the design of a trial (ERASE; NCT06093191) assessing the efficacy and safety of inhaled tobra...

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Bibliographic Details
Main Authors: Yong-Hua Gao, Hai-Wen Lu, Hui-Zhen Zheng, Chao Cao, De-Jie Chu, Hong Fan, Xiao-Yun Fan, Hong-Yan Gu, Wei-Jie Guan, Zhi-Jun Jie, Yang Jin, Wen Li, Yu-Ping Li, Yuan-Yuan Li, Lin Liu, Xue-Dong Liu, Hong Luo, Xiao-Dong Lv, Wei-Qiang Mo, Yuan-Lin Song, Dao-Xin Wang, Ling-Wei Wang, Chang-Zheng Wang, Min Xie, Min Zhang, Cui-Xia Zheng, Bei Mao, Sanjay H. Chotirmall, James D. Chalmers, Jie-Ming Qu, Jin-Fu Xu
Format: Article
Language:English
Published: European Respiratory Society 2024-02-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/10/1/00938-2023.full

Internet

http://openres.ersjournals.com/content/10/1/00938-2023.full

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