BoNT/A in the Urinary Bladder—More to the Story than Silencing of Cholinergic Nerves

Botulinum neurotoxin (BoNT/A) is an FDA and NICE approved second-line treatment for overactive bladder (OAB) in patients either not responsive or intolerant to anti-cholinergic drugs. BoNT/A acts to weaken muscle contraction by blocking release of the neurotransmitter acetyl choline (ACh) at neuromu...

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Bibliographic Details
Main Authors: Hodan Ibrahim, Jacquie Maignel, Fraser Hornby, Donna Daly, Matthew Beard
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/14/1/53