Characterization of the erythrocyte GTPase Rac1 in relation to Plasmodium falciparum invasion

Abstract Malaria is still a devastating disease with 228 million cases globally and 405,000 lethal outcomes in 2018, mainly in children under five years of age. The threat of emerging malaria strains resistant to currently available drugs has made the search for novel drug targets compelling. The pr...

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Bibliographic Details
Main Authors: Silvio Paone, Sarah D’Alessandro, Silvia Parapini, Francesco Celani, Valentina Tirelli, Manoochehr Pourshaban, Anna Olivieri
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79052-0