The role and mechanism of NRG1/ErbB4 in inducing the differentiation of induced pluripotent stem cells into cardiomyocytes

Abstract Background We aimed to investigate the effect and potential mechanism of enhancing Neuregulin1 (NRG1)/v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 (ErbB4) expression on the differentiation of induced pluripotent stem cells (iPSCs) into cardiomyocytes. Methods We utilized...

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Bibliographic Details
Main Authors: Xiaoou Li, Heng Zhang, Wenjing Li, Hu Tuo, Bing He, Hong Jiang
Format: Article
Language:English
Published: BMC 2024-10-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12872-024-04224-z