Pro-inflammatory interleukin-18 increases Alzheimer’s disease-associated amyloid-β production in human neuron-like cells
<p>Abstract</p> <p>Background</p> <p>Alzheimer’s disease (AD) involves increased accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles as well as neuronal loss in various regions of the neocortex. Neuroinflammation is also present, but its role in AD is not...
Main Authors: | Sutinen Elina M, Pirttilä Tuula, Anderson George, Salminen Antero, Ojala Johanna O |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-08-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://www.jneuroinflammation.com/content/9/1/199 |
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