Genome-wide ChIP-seq analysis of human TOP2B occupancy in MCF7 breast cancer epithelial cells

We report the whole genome ChIP seq for human TOP2B from MCF7 cells. Using three different peak calling methods, regions of binding were identified in the presence or absence of the nuclear hormone estradiol, as TOP2B has been reported to play a role in ligand-induced transcription. TOP2B peaks were...

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Bibliographic Details
Main Authors: Catriona M. Manville, Kayleigh Smith, Zbyslaw Sondka, Holly Rance, Simon Cockell, Ian G. Cowell, Ka Cheong Lee, Nicholas J. Morris, Kay Padget, Graham H. Jackson, Caroline A. Austin
Format: Article
Language:English
Published: The Company of Biologists 2015-11-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/4/11/1436