Identifying enhancer-driven subtype-specific prognostic markers in breast cancer based on multi-omics data

Identifying enhancer-driven subtype-specific prognostic markers in breast cancer based on multi-omics data

Breast cancer is a cancer of high complexity and heterogeneity, with differences in prognosis and survival among patients of different subtypes. Copy number variations (CNVs) within enhancers are crucial drivers of tumorigenesis by influencing expression of their targets. In this study, we performed...

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Bibliographic Details
Main Authors: Hongying Zhao, Siwen Zhang, Xiangzhe Yin, Caiyu Zhang, Lixia Wang, Kailai Liu, Haotian Xu, Wangyang Liu, Lin Bo, Shihua Lin, Ke Feng, Lin Lin, Meiting Fei, Shangwei Ning, Li Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
breast cancer subtype
enhancer
lncRNA
copy number variation
prognostic marker
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.990143/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.990143/full

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