In vitro oxygen imaging of acellular and cell-loaded beta cell replacement devices

Abstract Type 1 diabetes (T1D) is an autoimmune disease that leads to the loss of insulin-producing beta cells. Bioartificial pancreas (BAP) or beta cell replacement strategies have shown promise in curing T1D and providing long-term insulin independence. Hypoxia (low oxygen concentration) that may...

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Bibliographic Details
Main Authors: Mrignayani Kotecha, Longhai Wang, Safa Hameed, Navin Viswakarma, Minglin Ma, Cherie Stabler, Corinne A. Hoesli, Boris Epel
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42099-w