Multi‐omics analysis of disulfidptosis regulators and therapeutic potential reveals glycogen synthase 1 as a disulfidptosis triggering target for triple‐negative breast cancer

Multi‐omics analysis of disulfidptosis regulators and therapeutic potential reveals glycogen synthase 1 as a disulfidptosis triggering target for triple‐negative breast cancer

Abstract Disruption of disulfide homeostasis during biological processes can have fatal consequences. Excess disulfides induce cell death in a novel manner, termed as “disulfidptosis.” However, the specific mechanism of disulfidptosis has not yet been elucidated. To determine the cancer types sensit...

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Bibliographic Details
Main Authors: Jindong Xie, Xinpei Deng, Yi Xie, Hongbo Zhu, Peng Liu, Wei Deng, Li Ning, Yuhui Tang, Yuying Sun, Hailin Tang, Manbo Cai, Xiaoming Xie, Yutian Zou
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:MedComm
Subjects:
disulfidptosis
pan‐cancer
prognosis
single‐cell RNA‐seq
tumor microenvironment
Online Access:https://doi.org/10.1002/mco2.502

Internet

https://doi.org/10.1002/mco2.502

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