Melatonin as Modulator for Sulfur and Nitrogen Mustard-Induced Inflammation, Oxidative Stress and DNA Damage: Molecular Therapeutics

Melatonin as Modulator for Sulfur and Nitrogen Mustard-Induced Inflammation, Oxidative Stress and DNA Damage: Molecular Therapeutics

Sulfur and nitrogen mustards, bis(2-chloroethyl)sulfide and tertiary bis(2-chloroethyl) amines, respectively, are vesicant warfare agents with alkylating activity. Moreover, oxidative/nitrosative stress, inflammatory response induction, metalloproteinases activation, DNA damage or calcium disruption...

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Bibliographic Details
Main Authors: Eva Ramos, Emilio Gil-Martín, Cristóbal De Los Ríos, Javier Egea, Francisco López-Muñoz, René Pita, Antonio Juberías, Juan J. Torrado, Dolores R. Serrano, Russel J. Reiter, Alejandro Romero
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Antioxidants
Subjects:
sulfur and nitrogen mustard
melatonin
oxidative stress
melatonin metabolites
NLRP3 inflammasome
DNA damage
Online Access:https://www.mdpi.com/2076-3921/12/2/397

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https://www.mdpi.com/2076-3921/12/2/397

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