Abh, AbrB3, and Spo0A play distinct regulatory roles during polymyxin synthesis in Paenibacillus polymyxa SC2

Abh, AbrB3, and Spo0A play distinct regulatory roles during polymyxin synthesis in Paenibacillus polymyxa SC2

ABSTRACT Polymyxins exhibit antibacterial activity against various gram-negative bacteria. However, the regulatory mechanisms of polymyxin synthesis remain unclear. Here, Abh, AbrB3, and Spo0A of Paenibacillus polymyxa SC2 were found to bind to P pmx via DNA pull-down and electromagnetic mobility sh...

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Bibliographic Details
Main Authors: Yanru Cui, Dongying Zhao, Kai Liu, Xiangui Mei, Shanshan Sun, Binghai Du, Yanqin Ding
Format: Article
Language:English
Published: American Society for Microbiology 2024-01-01
Series:Microbiology Spectrum
Subjects:
polymyxin
Paenibacillus polymyxa
Abh
AbrB3
Spo0A
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02293-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.02293-23

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