Single-cell sequencing analysis and multiple machine-learning models revealed the cellular crosstalk of dendritic cells and identified FABP5 and KLRB1 as novel biomarkers for psoriasis

Single-cell sequencing analysis and multiple machine-learning models revealed the cellular crosstalk of dendritic cells and identified FABP5 and KLRB1 as novel biomarkers for psoriasis

BackgroundPsoriasis is an immune-mediated disorder influenced by environmental factors on a genetic basis. Despite advancements, challenges persist, including the diminishing efficacy of biologics and small-molecule targeted agents, alongside managing recurrence and psoriasis-related comorbidities....

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Bibliographic Details
Main Authors: Zhiqiang Ma, Pingyu An, Siyu Hao, Zhangxin Huang, Anqi Yin, Yuzhen Li, Jiangtian Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
single-cell sequencing analysis
machine learning
psoriasis
dendritic cell
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1374763/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1374763/full

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