Increased gene expression of CCR6 and RORγt in peripheral blood cells of rheumatoid arthritis patients and their correlation with anti‐cyclic citrullinated peptide and disease activity

Increased gene expression of CCR6 and RORγt in peripheral blood cells of rheumatoid arthritis patients and their correlation with anti‐cyclic citrullinated peptide and disease activity

Abstract Objectives The significance of T helper 17 (Th17) cells in the pathogenesis of rheumatoid arthritis (RA) has recently been demonstrated in many studies. Retinoic acid receptor‐related orphan receptor γt (RORγt) is a transcription factor that is specifically involved in the generation of Th1...

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Bibliographic Details
Main Authors: Seyed Askar Roghani, Ramin Lotfi, Masood Ghasemzade Soroush, Ali Khorasanizadeh, Parisa Feizollahi, Shirin Assar, Parviz Soufivand, Mehran Pournazari, Zahra Mohammadi Kish, Mahdi Taghadosi
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Immunity, Inflammation and Disease
Subjects:
anti‐CCP
CCR6
DAS‐28
rheumatoid arthritis
RORγt
Online Access:https://doi.org/10.1002/iid3.1112

Internet

https://doi.org/10.1002/iid3.1112

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