Structural basis for regulated assembly of the mitochondrial fission GTPase Drp1

Structural basis for regulated assembly of the mitochondrial fission GTPase Drp1

Abstract Mitochondrial fission is a critical cellular event to maintain organelle function. This multistep process is initiated by the enhanced recruitment and oligomerization of dynamin-related protein 1 (Drp1) at the surface of mitochondria. As such, Drp1 is essential for inducing mitochondrial di...

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Bibliographic Details
Main Authors: Kristy Rochon, Brianna L. Bauer, Nathaniel A. Roethler, Yuli Buckley, Chih-Chia Su, Wei Huang, Rajesh Ramachandran, Maria S. K. Stoll, Edward W. Yu, Derek J. Taylor, Jason A. Mears
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45524-4

Internet

https://doi.org/10.1038/s41467-024-45524-4

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