Metabolic Alterations in Multiple Myeloma: From Oncogenesis to Proteasome Inhibitor Resistance

Metabolic Alterations in Multiple Myeloma: From Oncogenesis to Proteasome Inhibitor Resistance

Despite significant improvements in treatment strategies over the past couple of decades, multiple myeloma (MM) remains an incurable disease due to the development of drug resistance. Metabolic reprogramming is a key feature of cancer cells, including MM, and acts to fuel increased proliferation, cr...

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Bibliographic Details
Main Authors: Philip Weir, David Donaldson, Mary Frances McMullin, Lisa Crawford
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cancers
Subjects:
multiple myeloma
cellular metabolism
proteasome inhibitors
drug resistance
Online Access:https://www.mdpi.com/2072-6694/15/6/1682

Internet

https://www.mdpi.com/2072-6694/15/6/1682

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