DHEA and Its Metabolites Reduce the Cytokines Involved in the Inflammatory Response and Fibrosis in Primary Biliary Cholangitis

DHEA and Its Metabolites Reduce the Cytokines Involved in the Inflammatory Response and Fibrosis in Primary Biliary Cholangitis

Dehydroepiandrosterone (DHEA) is an abundant steroid and precursor of sex hormones. During aging, the reduction in DHEA synthesis causes a significant depletion of estrogens and androgens in different organs, such as the ovaries, brain, and liver. Primary Biliary Cholangitis (PBC) is a cholestatic l...

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Bibliographic Details
Main Authors: Małgorzata Blatkiewicz, Katarzyna Sielatycka, Katarzyna Piotrowska, Ewa Kilańczyk
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
DHEA
interleukins
estrogens
steroidogenesis
PBC
Online Access:https://www.mdpi.com/1422-0067/24/6/5301

Internet

https://www.mdpi.com/1422-0067/24/6/5301

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