Next-generation sequencing profiling of miRNAs in individuals with 22q11.2 deletion syndrome revealed altered expression of miR-185-5p

Next-generation sequencing profiling of miRNAs in individuals with 22q11.2 deletion syndrome revealed altered expression of miR-185-5p

Abstract Background The 22q11.2 deletion syndrome (22q11.2DS) is a microdeletion syndrome with highly variable phenotypic manifestations, even though most patients present the typical 3 Mb microdeletion, usually affecting the same ~ 106 genes. One of the genes affected by this deletion is DGCR8, whi...

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Bibliographic Details
Main Authors: Anelisa Gollo Dantas, Beatriz Carvalho Nunes, Natália Nunes, Pedro Galante, Paula Fontes Asprino, Vanessa Kiyomi Ota, Maria Isabel Melaragno
Format: Article
Language:English
Published: BMC 2024-06-01
Series:Human Genomics
Subjects:
22q11.2 deletion syndrome
miRNA
Next-generation sequencing
miR-185-5p
Online Access:https://doi.org/10.1186/s40246-024-00625-5

Internet

https://doi.org/10.1186/s40246-024-00625-5

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