Targeting bacterial growth in biofilm conditions: rational design of novel inhibitors to mitigate clinical and food contamination using QSAR

Targeting bacterial growth in biofilm conditions: rational design of novel inhibitors to mitigate clinical and food contamination using QSAR

AbstractAntimicrobial resistance (AMR) is a pressing global issue exacerbated by the abuse of antibiotics and the formation of bacterial biofilms, which cause up to 80% of human bacterial infections. This study presents a computational strategy to address AMR by developing three novel quantitative s...

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Bibliographic Details
Main Authors: Maria Galvez-Llompart, Jesús Hierrezuelo, Mariluz Blasco, Riccardo Zanni, Jorge Galvez, Antonio de Vicente, Alejandro Pérez-García, Diego Romero
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Biofilm
bacteria
antimicrobial
molecular topology
QSAR
food safety
Online Access:https://www.tandfonline.com/doi/10.1080/14756366.2024.2330907

Internet

https://www.tandfonline.com/doi/10.1080/14756366.2024.2330907

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