Recent advances in understanding the regulation of metalloproteinases [version 1; referees: 2 approved]
Metalloproteinases remain important players in arthritic disease, in part because members of this large enzymatic family, namely matrix metalloproteinase-1 (MMP-1) and MMP-13, are responsible for the irreversible degradation of articular cartilage collagen. Although direct inhibition of MMPs fell ou...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2019-02-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/8-195/v1 |