Severe T-System Remodeling in Pediatric Viral Myocarditis

Severe T-System Remodeling in Pediatric Viral Myocarditis

Chronic heart failure (HF) in adults causes remodeling of the cardiomyocyte transverse tubular system (t-system), which contributes to disease progression by impairing excitation-contraction (EC) coupling. However, it is unknown if t-system remodeling occurs in pediatric heart failure. This study in...

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Bibliographic Details
Main Authors: Dominik J. Fiegle, Martin Schöber, Sven Dittrich, Robert Cesnjevar, Karin Klingel, Tilmann Volk, Muhannad Alkassar, Thomas Seidel
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
myocarditis
transverse tubular system
excitation-contracting coupling
heart failiure
remodeling
confocal micoscopy
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2020.624776/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2020.624776/full

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