Use of autoantigen-loaded phosphatidylserine-liposomes to arrest autoimmunity in type 1 diabetes.

INTRODUCTION:The development of new therapies to induce self-tolerance has been an important medical health challenge in type 1 diabetes. An ideal immunotherapy should inhibit the autoimmune attack, avoid systemic side effects and allow β-cell regeneration. Based on the immunomodulatory effects of a...

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Main Authors: Irma Pujol-Autonell, Arnau Serracant-Prat, Mary Cano-Sarabia, Rosa M Ampudia, Silvia Rodriguez-Fernandez, Alex Sanchez, Cristina Izquierdo, Thomas Stratmann, Manuel Puig-Domingo, Daniel Maspoch, Joan Verdaguer, Marta Vives-Pi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0127057