Postmortem imaging reveals patterns of medial temporal lobe vulnerability to tau pathology in Alzheimer’s disease

Postmortem imaging reveals patterns of medial temporal lobe vulnerability to tau pathology in Alzheimer’s disease

Abstract Our current understanding of the spread and neurodegenerative effects of tau neurofibrillary tangles (NFTs) within the medial temporal lobe (MTL) during the early stages of Alzheimer’s Disease (AD) is limited by the presence of confounding non-AD pathologies and the two-dimensional (2-D) na...

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Bibliographic Details
Main Authors: Sadhana Ravikumar, Amanda E. Denning, Sydney Lim, Eunice Chung, Niyousha Sadeghpour, Ranjit Ittyerah, Laura E. M. Wisse, Sandhitsu R. Das, Long Xie, John L. Robinson, Theresa Schuck, Edward B. Lee, John A. Detre, M. Dylan Tisdall, Karthik Prabhakaran, Gabor Mizsei, Maria Mercedes Iñiguez de Onzono Martin, Maria del Mar Arroyo Jiménez, Monica Mũnoz, Maria del Pilar Marcos Rabal, Sandra Cebada Sánchez, José Carlos Delgado González, Carlos de la Rosa Prieto, David J. Irwin, David A. Wolk, Ricardo Insausti, Paul A. Yushkevich
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-49205-0

Internet

https://doi.org/10.1038/s41467-024-49205-0

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