Extensive evaluation of ATAC-seq protocols for native or formaldehyde-fixed nuclei

Abstract Background The “Assay for Transposase Accessible Chromatin sequencing” (ATAC-seq) is an efficient and easy to implement protocol to measure chromatin accessibility that has been widely used in multiple applications studying gene regulation. While several modifications or variants of the pro...

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Bibliographic Details
Main Authors: Hao Zhang, Michael E. Rice, Joseph W. Alvin, Dominique Farrera-Gaffney, James J. Galligan, Michael D. L. Johnson, Darren A. Cusanovich
Format: Article
Language:English
Published: BMC 2022-03-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-021-08266-x