Synthesis, Spectral Characterization and Biological Activities of Co(II) and Ni(II) Mixed Ligand Complexes
2,4-Dinitrophynylhydrazine and two thiocyanate ions in a (M:L1:L2) 1:2:2 molar ratio was synthesized in the complexes of Co(II) and Ni(II). The prepared compounds were identified through a C.H.N.S. analysis, conductivity measurements, powder X-ray diffraction (PXRD), the infrared spectrum, and a UV-...
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MDPI AG
2021-02-01
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| author | P. Manimaran S. Balasubramaniyan Mohammad Azam D. Rajadurai Saud I. Al-Resayes G. Mathubala A. Manikandan S. Muthupandi Zishan Tabassum Imran Khan |
| author_facet | P. Manimaran S. Balasubramaniyan Mohammad Azam D. Rajadurai Saud I. Al-Resayes G. Mathubala A. Manikandan S. Muthupandi Zishan Tabassum Imran Khan |
| author_sort | P. Manimaran |
| collection | DOAJ |
| description | 2,4-Dinitrophynylhydrazine and two thiocyanate ions in a (M:L1:L2) 1:2:2 molar ratio was synthesized in the complexes of Co(II) and Ni(II). The prepared compounds were identified through a C.H.N.S. analysis, conductivity measurements, powder X-ray diffraction (PXRD), the infrared spectrum, and a UV-visible spectrum analysis, in addition to the magnetic properties being measured. The measurements of the molar conductance implieda nonelectrolytic nature of compounds Co(II) and Ni(II). The magnetic susceptibility, as well as electronic spectra, represented all the metal complexesthroughoctahedral geometry, respectively. The PXRD patterns suggested that all the complexes were an orthorhombic system with unit cell parameters. The in-vitro biological activity of the ligand and the metal complexes were screened against the Gram-positive and negative pathogenic bacteria Staphylococcus aureus, Bacillus subtilis, <i>Pseudomonas</i>, <i>aeruginosa</i> and <i>Escherichia coli</i>, as well as the fungal species of <i>Aspergillusniger</i> and <i>Candida albicans</i>.Thus, the metal complexes showeda high efficiency of antimicrobial activity compared with the ligand. Furthermore, applications of the ligand, as well as the metal complexes, were tested for in-vitro antioxidant potential in aDPPH assay. The results showed that the activity of the metal complexes with the in-vitro antioxidant was more active than that of 2,4-dinitrophenylhydrazine(DNPH). |
| first_indexed | 2024-03-09T05:35:09Z |
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| language | English |
| last_indexed | 2024-03-09T05:35:09Z |
| publishDate | 2021-02-01 |
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| series | Molecules |
| spelling | doaj.art-0571e04c1e204d96835d82b4a63921e02023-12-03T12:29:13ZengMDPI AGMolecules1420-30492021-02-0126482310.3390/molecules26040823Synthesis, Spectral Characterization and Biological Activities of Co(II) and Ni(II) Mixed Ligand ComplexesP. Manimaran0S. Balasubramaniyan1Mohammad Azam2D. Rajadurai3Saud I. Al-Resayes4G. Mathubala5A. Manikandan6S. Muthupandi7Zishan Tabassum8Imran Khan9PG & Research Department of Chemistry, Government Arts College, Ariyalur 621713, IndiaPG & Research Department of Chemistry, Government Arts College, Ariyalur 621713, IndiaDepartment of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi ArabiaDepartment of Chemistry, Government Arts College (Autonomous), Karur 639005, IndiaDepartment of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi ArabiaDepartment of Chemistry, Bharath Institute of Higher Education and Research, Selaiyur, Chennai 600073, IndiaDepartment of Chemistry, Bharath Institute of Higher Education and Research, Selaiyur, Chennai 600073, IndiaDepartment of Physics, Loyola College, Affiliated to University of Madras, Chennai 600034, IndiaDepartment of Chemistry, Rajshree Institute of Management and Technology, Bareilly 243122, IndiaApplied Science Humanities Section, University Polytechnic, Faculty of Engineering and Technology, Aligarh Muslim University, Aligarh 202002, India2,4-Dinitrophynylhydrazine and two thiocyanate ions in a (M:L1:L2) 1:2:2 molar ratio was synthesized in the complexes of Co(II) and Ni(II). The prepared compounds were identified through a C.H.N.S. analysis, conductivity measurements, powder X-ray diffraction (PXRD), the infrared spectrum, and a UV-visible spectrum analysis, in addition to the magnetic properties being measured. The measurements of the molar conductance implieda nonelectrolytic nature of compounds Co(II) and Ni(II). The magnetic susceptibility, as well as electronic spectra, represented all the metal complexesthroughoctahedral geometry, respectively. The PXRD patterns suggested that all the complexes were an orthorhombic system with unit cell parameters. The in-vitro biological activity of the ligand and the metal complexes were screened against the Gram-positive and negative pathogenic bacteria Staphylococcus aureus, Bacillus subtilis, <i>Pseudomonas</i>, <i>aeruginosa</i> and <i>Escherichia coli</i>, as well as the fungal species of <i>Aspergillusniger</i> and <i>Candida albicans</i>.Thus, the metal complexes showeda high efficiency of antimicrobial activity compared with the ligand. Furthermore, applications of the ligand, as well as the metal complexes, were tested for in-vitro antioxidant potential in aDPPH assay. The results showed that the activity of the metal complexes with the in-vitro antioxidant was more active than that of 2,4-dinitrophenylhydrazine(DNPH).https://www.mdpi.com/1420-3049/26/4/823mixed-ligand complexesDNPHantimicrobialDPPH assay |
| spellingShingle | P. Manimaran S. Balasubramaniyan Mohammad Azam D. Rajadurai Saud I. Al-Resayes G. Mathubala A. Manikandan S. Muthupandi Zishan Tabassum Imran Khan Synthesis, Spectral Characterization and Biological Activities of Co(II) and Ni(II) Mixed Ligand Complexes Molecules mixed-ligand complexes DNPH antimicrobial DPPH assay |
| title | Synthesis, Spectral Characterization and Biological Activities of Co(II) and Ni(II) Mixed Ligand Complexes |
| title_full | Synthesis, Spectral Characterization and Biological Activities of Co(II) and Ni(II) Mixed Ligand Complexes |
| title_fullStr | Synthesis, Spectral Characterization and Biological Activities of Co(II) and Ni(II) Mixed Ligand Complexes |
| title_full_unstemmed | Synthesis, Spectral Characterization and Biological Activities of Co(II) and Ni(II) Mixed Ligand Complexes |
| title_short | Synthesis, Spectral Characterization and Biological Activities of Co(II) and Ni(II) Mixed Ligand Complexes |
| title_sort | synthesis spectral characterization and biological activities of co ii and ni ii mixed ligand complexes |
| topic | mixed-ligand complexes DNPH antimicrobial DPPH assay |
| url | https://www.mdpi.com/1420-3049/26/4/823 |
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