Salmonella exploits LRRK2-dependent plasma membrane dynamics to invade host cells

Salmonella exploits LRRK2-dependent plasma membrane dynamics to invade host cells

Abstract Salmonella utilizes type 3 secreted effector proteins to induce plasma membrane (PM) perturbations during invasion of host cells1. The effectors drive mobilization of host membranes to generate cell surface ruffles, followed by invagination and scission of the PM to generate Salmonella-cont...

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Bibliographic Details
Main Authors: Hongxian Zhu, Andrew M. Sydor, Bing-Ru Yan, Ren Li, Michal T. Boniecki, Carina Lyons, Miroslaw Cygler, Aleixo M. Muise, Michelle E. Maxson, Sergio Grinstein, Brian Raught, John H. Brumell
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57453-x

Internet

https://doi.org/10.1038/s41467-025-57453-x

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