Defining Patient-Level Molecular Heterogeneity in Psoriasis Vulgaris Based on Single-Cell Transcriptomics

Defining Patient-Level Molecular Heterogeneity in Psoriasis Vulgaris Based on Single-Cell Transcriptomics

Identifying genetic variation underlying human diseases establishes targets for therapeutic development and helps tailor treatments to individual patients. Large-scale transcriptomic profiling has extended the study of such molecular heterogeneity between patients to somatic tissues. However, the lo...

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Bibliographic Details
Main Authors: Yale Liu, Hao Wang, Christopher Cook, Mark A. Taylor, Jeffrey P. North, Ashley Hailer, Yanhong Shou, Arsil Sadik, Esther Kim, Elizabeth Purdom, Jeffrey B. Cheng, Raymond J. Cho
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
single-cell RNA-sequencing
psoriasis vulgaris
heterogeneity
cytoskeleton
chromatin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.842651/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.842651/full

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