Exogenous oxygen is required for prostanoid induction under brain ischemia as evidence for a novel regulatory mechanism

Exogenous oxygen is required for prostanoid induction under brain ischemia as evidence for a novel regulatory mechanism

Previously, we and others reported a rapid and dramatic increase in brain prostanoids (PG), including prostaglandins, prostacyclins, and thromboxanes, under ischemia that is traditionally explained through the activation of esterified arachidonic acid (20:4n6) release by phospholipases as a substrat...

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Bibliographic Details
Main Authors: Drew R. Seeger, Brennon Schofield, Derek Besch, Svetlana A. Golovko, Peddanna Kotha, Meredith Parmer, Shahram Solaymani-Mohammadi, Mikhail Y. Golovko
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Journal of Lipid Research
Subjects:
arachidonic acid
prostaglandins
cyclooxygenase
oxidized lipids
brain lipids
phopsholipids
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227523001256

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http://www.sciencedirect.com/science/article/pii/S0022227523001256

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