Nephrectomy and peritoneal dialysis eliminates circulating renin and controls uraemia in the rat

Objective The aim of the present study was to develop a rat model for in vivo studies of the local effects of the renin-angiotensin system (RAS) following elimination of circulating renin. Methods Sprague Dawley rats were bilaterally nephrectomised and had a peritoneal dialysis catheter implanted. T...

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Bibliographic Details
Main Authors: Trine Fischer Pedersen, Arne Høj Nielsen, Svend Strandgaard, Olaf B Paulson
Format: Article
Language:English
Published: SAGE Publications 2002-06-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2002.015