Polygenic risk scores across the extended psychosis spectrum

Polygenic risk scores across the extended psychosis spectrum

Abstract As early detection of symptoms in the subclinical to clinical psychosis spectrum may improve health outcomes, knowing the probabilistic susceptibility of developing a disorder could guide mitigation measures and clinical intervention. In this context, polygenic risk scores (PRSs) quantifyin...

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Main Authors: Lukasz Smigielski, Sergi Papiol, Anastasia Theodoridou, Karsten Heekeren, Miriam Gerstenberg, Diana Wotruba, Roman Buechler, Per Hoffmann, Stefan Herms, Kristina Adorjan, Heike Anderson-Schmidt, Monika Budde, Ashley L. Comes, Katrin Gade, Maria Heilbronner, Urs Heilbronner, Janos L. Kalman, Farahnaz Klöhn-Saghatolislam, Daniela Reich-Erkelenz, Sabrina K. Schaupp, Eva C. Schulte, Fanny Senner, Ion-George Anghelescu, Volker Arolt, Bernhard T. Baune, Udo Dannlowski, Detlef E. Dietrich, Andreas J. Fallgatter, Christian Figge, Markus Jäger, Georg Juckel, Carsten Konrad, Vanessa Nieratschker, Jens Reimer, Eva Reininghaus, Max Schmauß, Carsten Spitzer, Martin von Hagen, Jens Wiltfang, Jörg Zimmermann, Anna Gryaznova, Laura Flatau-Nagel, Markus Reitt, Milena Meyers, Barbara Emons, Ida Sybille Haußleiter, Fabian U. Lang, Thomas Becker, Moritz E. Wigand, Stephanie H. Witt, Franziska Degenhardt, Andreas J. Forstner, Marcella Rietschel, Markus M. Nöthen, Till F. M. Andlauer, Wulf Rössler, Susanne Walitza, Peter Falkai, Thomas G. Schulze, Edna Grünblatt
Format: Article
Language:English
Published: Nature Publishing Group 2021-11-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01720-0

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https://doi.org/10.1038/s41398-021-01720-0

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