HIV-1 Vpr protein upregulates microRNA-210-5p expression to induce G2 arrest by targeting TGIF2.

HIV-1 Vpr protein upregulates microRNA-210-5p expression to induce G2 arrest by targeting TGIF2.

MicroRNAs (miRNAs) are important molecules that mediate virus-host interactions, mainly by regulating gene expression via gene silencing. Here, we demonstrated that HIV-1 infection upregulated miR-210-5p in HIV-1-inoculated cell lines and in the serum of HIV-1-infected individuals. Luciferase report...

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Bibliographic Details
Main Authors: Jialu Qiao, Qian Peng, Feng Qian, Qiang You, Lingyan Feng, Song Hu, Wei Liu, Lixia Huang, Xiji Shu, Binlian Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0261971

Internet

https://doi.org/10.1371/journal.pone.0261971

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