N-acetyl-aspartate and Myo-inositol as Markers of White Matter Microstructural Organization in Mild Cognitive Impairment: Evidence from a DTI-<sup>1</sup>H-MRS Pilot Study

N-acetyl-aspartate and Myo-inositol as Markers of White Matter Microstructural Organization in Mild Cognitive Impairment: Evidence from a DTI-<sup>1</sup>H-MRS Pilot Study

We implemented a multimodal approach to examine associations between structural and neurochemical changes that could signify neurodegenerative processes related to mild cognitive impairment (MCI). Fifty-nine older adults (60–85 years; 22 MCI) underwent whole-brain structural 3T MRI (T1W, T2W, DTI) a...

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Bibliographic Details
Main Authors: Kristina Valatkevičienė, Oron Levin, Milda Šarkinaitė, Wouter A. J. Vints, Rimantė Kunickaitė, Greta Danylė, Simona Kušleikienė, Samrat Sheoran, Vida J. Česnaitienė, Nerijus Masiulis, Uwe Himmelreich, Rymantė Gleiznienė
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Diagnostics
Subjects:
MR spectroscopy
DTI
aging
cognition
mild cognitive impairment
Online Access:https://www.mdpi.com/2075-4418/13/4/654

Internet

https://www.mdpi.com/2075-4418/13/4/654

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