Is age a risk factor for liver disease and metabolic alterations in ataxia Telangiectasia patients?

Is age a risk factor for liver disease and metabolic alterations in ataxia Telangiectasia patients?

Abstract Background Ataxia telangiectasia (A-T) is a neurodegenerative disease that leads to mitochondrial dysfunction and oxidative stress. Insulin resistance (IR), type 2 diabetes and the risk for development of cardiovascular disease was recently associated as an extended phenotype of the disease...

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Bibliographic Details
Main Authors: Talita Lemos Paulino, Marina Neto Rafael, Sonia Hix, David Carlos Shigueoka, Sergio Aron Ajzen, Cristiane Kochi, Fabíola Isabel Suano-Souza, Rosangela da Silva, Beatriz T. Costa-Carvalho, Roseli O. S. Sarni
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Ataxia Telangiectasia
Atherosclerosis
Carotid Intima-media thickness
Insulin resistance
Fatty liver disease
Dyslipidemia
Online Access:http://link.springer.com/article/10.1186/s13023-017-0689-y

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http://link.springer.com/article/10.1186/s13023-017-0689-y

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