Hyperoside ameliorates cerebral ischaemic–reperfusion injury by opening the TRPV4 channel in vivo through the IP3-PKC signalling pathway

Hyperoside ameliorates cerebral ischaemic–reperfusion injury by opening the TRPV4 channel in vivo through the IP3-PKC signalling pathway

AbstractContext Hyperoside (Hyp), one of the active flavones from Rhododendron (Ericaceae), has beneficial effects against cerebrovascular disease. However, the effect of Hyp on vasodilatation has not been elucidated.Objective To explore the effect of Hyp on vasodilatation in the cerebral basilar ar...

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Bibliographic Details
Main Authors: Lei Shi, Chenchen Jiang, Hanghang Xu, Jiangping Wu, Jiajun Lu, Yuxiang He, Xiuyun Yin, Zhuo Chen, Di Cao, Xuebin Shen, Xuefeng Hou, Jun Han
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Pharmaceutical Biology
Subjects:
Traditional Chinese medicine
ischaemic stroke
cerebral vasodilation
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2023.2228379

Internet

https://www.tandfonline.com/doi/10.1080/13880209.2023.2228379

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