Loss of Mature Lamin A/C Triggers a Shift in Intracellular Metabolic Homeostasis via AMPKα Activation

Loss of Mature Lamin A/C Triggers a Shift in Intracellular Metabolic Homeostasis via AMPKα Activation

The roles of lamin A/C in adipocyte differentiation and skeletal muscle lipid metabolism are associated with familial partial lipodystrophy of Dunnigan (FPLD). We confirmed that <i>LMNA</i> knockdown (KD) in mouse adipose-derived mesenchymal stem cells (AD-MSCs) prevented adipocyte matur...

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Bibliographic Details
Main Authors: Ying Zhou, Jia-Jie Yang, Yuan Cheng, Ge-Xuan Feng, Rong-Hui Yang, Yuan Yuan, Li-Yong Wang, Miao Wang, Lu Kong
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
<i>LMNA</i>
AMPK
lipid metabolism
hepatocellular carcinoma
Online Access:https://www.mdpi.com/2073-4409/11/24/3988

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https://www.mdpi.com/2073-4409/11/24/3988

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