Striatal dopamine D2/3 receptor availability in treatment resistant depression.

Several studies demonstrated improvement of depressive symptoms in treatment resistant depression (TRD) after administering dopamine agonists which suggest abnormal dopaminergic neurotransmission in TRD. However, the role of dopaminergic signaling through measurement of striatal dopamine D(2/3) rece...

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Bibliographic Details
Main Authors: Bart P de Kwaasteniet, Chedwa Pinto, Henricus G Ruhé, Guido A van Wingen, Jan Booij, Damiaan Denys
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4239080?pdf=render