Behavioral Effects of Systemic, Infralimbic and Prelimbic Injections of a Serotonin 5-HT2A Antagonist in Carioca High- and Low-Conditioned Freezing Rats

Behavioral Effects of Systemic, Infralimbic and Prelimbic Injections of a Serotonin 5-HT2A Antagonist in Carioca High- and Low-Conditioned Freezing Rats

The role of serotonin (5-hydroxytryptamine [5-HT]) and 5-HT2A receptors in anxiety has been extensively studied, mostly without considering individual differences in trait anxiety. Our laboratory developed two lines of animals that are bred for high and low freezing responses to contextual cues that...

Full description

Bibliographic Details
Main Authors: Laura A. León, Vitor Castro-Gomes, Santiago Zárate-Guerrero, Karen Corredor, Antonio P. Mello Cruz, Marcus L. Brandão, Fernando P. Cardenas, J. Landeira-Fernandez
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
breeding lines
freezing
contextual fear conditioning
elevated plus maze
serotonin
5-HT2A receptors
Online Access:http://journal.frontiersin.org/article/10.3389/fnbeh.2017.00117/full

Internet

http://journal.frontiersin.org/article/10.3389/fnbeh.2017.00117/full

Similar Items