Development of Highly Functional Long-Term Culture Method of Liver Slice Embedded in Agarose Gel for Bioartificial Liver

It is difficult to a produce highly functional bioartificial liver (BAL) using only hepatocytes, because it is believed that liver-specific three-dimensional structure is necessary to maintain high function for BAL. But it is difficult to construct a culture system with liver-specific three-dimensio...

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Bibliographic Details
Main Authors: Hideki Nonaka, Hirohiko Ise, Nobuhiro Sugihara, Shinichi Hirose, Naoki Negishi, Yoshiyuki Kondo, Toshihiro Akaike
Format: Article
Language:English
Published: SAGE Publishing 2003-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000003108747055