Longitudinal study of cross-reactive antigenemia in individuals with high Loa loa microfilarial density reveals promising biomarkers for distinguishing lymphatic filariasis from loiasis

Longitudinal study of cross-reactive antigenemia in individuals with high Loa loa microfilarial density reveals promising biomarkers for distinguishing lymphatic filariasis from loiasis

Background and methodsCirculating Loa loa antigens are often detected in individuals with heavy L. loa infections by diagnostic tests for lymphatic filariasis (LF) caused by Wuchereria bancrofti. This is a major challenge to LF mapping and elimination efforts in loiasis co-endemic areas. However, it...

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Bibliographic Details
Main Authors: Linda Djune-Yemeli, Marla Hertz, Hugues C. Nana-Djeunga, Amy Rush, Petra Erdmann-Gilmore, Robert Sprung, Jean Gabin Bopda, Reid Townsend, Palmer Masumbe Netongo, Joseph Kamgno, Philip J. Budge
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Parasitology
Subjects:
Loiasis
lymphatic filariasis
cross-reactivity
LF-rapid diagnostic tests
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fpara.2023.1292837/full

Internet

https://www.frontiersin.org/articles/10.3389/fpara.2023.1292837/full

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