Prediction of Phytochemicals for Their Potential to Inhibit New Delhi Metallo β-Lactamase (NDM-1)

Prediction of Phytochemicals for Their Potential to Inhibit New Delhi Metallo β-Lactamase (NDM-1)

The effectiveness of all antibiotics in the β-lactam group to cure bacterial infections has been impaired by the introduction of the New Delhi Metallo-β-lactamase (NDM-1) enzyme. Attempts have been made to discover a potent chemical as an inhibitor to this enzyme in order to restore the efficacy of...

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Bibliographic Details
Main Authors: Zainab Bibi, Irfa Asghar, Naeem Mahmood Ashraf, Iftikhar Zeb, Umer Rashid, Arslan Hamid, Maria Kanwal Ali, Ashraf Atef Hatamleh, Munirah Abdullah Al-Dosary, Raza Ahmad, Muhammad Ali
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Pharmaceuticals
Subjects:
New Delhi metallo β-lactamase-1
phytochemicals
polyphenols
molecular dynamics simulations
metallo β-lactamase inhibitors
Online Access:https://www.mdpi.com/1424-8247/16/10/1404

Internet

https://www.mdpi.com/1424-8247/16/10/1404

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