The Roles of Immunoregulatory Networks in Severe Drug Hypersensitivity

The Roles of Immunoregulatory Networks in Severe Drug Hypersensitivity

The immunomodulatory effects of regulatory T cells (Tregs) and co-signaling receptors have gained much attention, as they help balance immunogenic and immunotolerant responses that may be disrupted in autoimmune and infectious diseases. Drug hypersensitivity has a myriad of manifestations, which ran...

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Bibliographic Details
Main Authors: Yun-Shiuan Olivia Hsu, Kun-Lin Lu, Yun Fu, Chuang-Wei Wang, Chun-Wei Lu, Yu-Fen Lin, Wen-Cheng Chang, Kun-Yun Yeh, Shuen-Iu Hung, Wen-Hung Chung, Chun-Bing Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
contact dermatitis
delayed type hypersensitivity
drug reaction with eosinophilia and systemic symptoms
cosignaling pathways
immune checkpoints
regulatory T cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.597761/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.597761/full

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