Active DNA demethylation—The epigenetic gatekeeper of development, immunity, and cancer

Abstract DNA methylation is a critical process in the regulation of gene expression with dramatic effects in development and continually expanding roles in oncogenesis. 5‐Methylcytosine was once considered to be an inherited and stably repressive epigenetic mark, which can be only removed by passive...

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Bibliographic Details
Main Authors: Rahul Prasad, Timothy J. Yen, Alfonso Bellacosa
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Advanced Genetics
Subjects:
Online Access:https://doi.org/10.1002/ggn2.10033