CRISPR/Cas9-based Engineering of Immunoglobulin Loci in Hybridoma Cells

Development of the hybridoma technology by Köhler and Milstein (1975) has revolutionized the immunological field by enabling routine use of monoclonal antibodies (mAbs) in research and development efforts, resulting in their successful application in the clinic today. While recombinant good manufact...

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Bibliografski detalji
Glavni autori: Camille Le Gall, Felix Fennemann, Johan van der Schoot, Ferenc Scheeren, Martijn Verdoes
Format: Članak
Jezik:English
Izdano: Bio-protocol LLC 2023-02-01
Serija:Bio-Protocol
Online pristup:https://bio-protocol.org/en/bpdetail?id=4613&type=0