Baculovirus-Free SARS-CoV-2 Virus-like Particle Production in Insect Cells for Rapid Neutralization Assessment

Baculovirus-Free SARS-CoV-2 Virus-like Particle Production in Insect Cells for Rapid Neutralization Assessment

Virus-like particles (VLPs) resemble authentic virus while not containing any genomic information. Here, we present a fast and powerful method for the production of SARS-CoV-2 VLP in insect cells and the application of these VLPs to evaluate the inhibition capacity of monoclonal antibodies and sera...

Full description

Bibliographic Details
Main Authors: Marcel Jaron, Michael Lehky, Marta Zarà, Chris Nicole Zaydowicz, Aidin Lak, Rico Ballmann, Philip Alexander Heine, Esther Veronika Wenzel, Kai-Thomas Schneider, Federico Bertoglio, Susanne Kempter, Reinhard Wolfgang Köster, Silvia Stella Barbieri, Joop van den Heuvel, Michael Hust, Stefan Dübel, Maren Schubert
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Viruses
Subjects:
virus-like particles (VLPs)
SARS-CoV-2
insect cells
expression vector
antibodies
cellular assay
Online Access:https://www.mdpi.com/1999-4915/14/10/2087

Internet

https://www.mdpi.com/1999-4915/14/10/2087

Similar Items