Cell-Permeable Peptide Blocks TLR4 Signaling and Improves Islet Allograft Survival
Toll-like receptor 4 (TLR4) activation in pancreatic β cells activates aberrant islet graft cellular pathways and contributes to immune rejection in allogeneic islet transplantation. As an approach to overcoming this problem, we determined the capacity of a 33-amino acid peptide consisting of a prot...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2016-07-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368916X690449 |