Cell-Permeable Peptide Blocks TLR4 Signaling and Improves Islet Allograft Survival

Cell-Permeable Peptide Blocks TLR4 Signaling and Improves Islet Allograft Survival

Toll-like receptor 4 (TLR4) activation in pancreatic β cells activates aberrant islet graft cellular pathways and contributes to immune rejection in allogeneic islet transplantation. As an approach to overcoming this problem, we determined the capacity of a 33-amino acid peptide consisting of a prot...

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Bibliographic Details
Main Authors:	Huansheng Dong, Yong Zhang, Lili Song, Do-Sung Kim, Hongju Wu, Lijun Yang, Shiwu Li, Katherine A. Morgan, David B. Adams, Hongjun Wang Ph.D.
Format:	Article
Language:	English
Published:	SAGE Publishing 2016-07-01
Series:	Cell Transplantation
Online Access:	https://doi.org/10.3727/096368916X690449

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