The CD14+CD16+ inflammatory monocyte subset displays increased mitochondrial activity and effector function during acute Plasmodium vivax malaria.

The CD14+CD16+ inflammatory monocyte subset displays increased mitochondrial activity and effector function during acute Plasmodium vivax malaria.

Infection with Plasmodium vivax results in strong activation of monocytes, which are important components of both the systemic inflammatory response and parasite control. The overall goal of this study was to define the role of monocytes during P. vivax malaria. Here, we demonstrate that P. vivax-in...

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Bibliographic Details
Main Authors: Lis R V Antonelli, Fabiana M S Leoratti, Pedro A C Costa, Bruno C Rocha, Suelen Q Diniz, Mauro S Tada, Dhelio B Pereira, Andrea Teixeira-Carvalho, Douglas T Golenbock, Ricardo Gonçalves, Ricardo T Gazzinelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4169496?pdf=render

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http://europepmc.org/articles/PMC4169496?pdf=render

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