Ameloblastin inhibits cranial suture closure by modulating MSX2 expression and proliferation.

Deformities of cranial sutures such as craniosynostosis and enlarged parietal foramina greatly impact human development and quality of life. Here we have examined the role of the extracellular matrix protein ameloblastin (Ambn), a recent addition to the family of non-collagenous extracellular bone m...

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Bibliographic Details
Main Authors: Phimon Atsawasuwan, Xuanyu Lu, Yoshihiro Ito, Youbin Zhang, Carla A Evans, Xianghong Luan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3617155?pdf=render