CXCL14 deficiency in mice attenuates obesity and inhibits feeding behavior in a novel environment.

CXCL14 deficiency in mice attenuates obesity and inhibits feeding behavior in a novel environment.

BACKGROUND: CXCL14 is a chemoattractant for macrophages and immature dendritic cells. We recently reported that CXCL14-deficient (CXCL14(-/-)) female mice in the mixed background are protected from obesity-induced hyperglycemia and insulin resistance. The decreased macrophage infiltration into visce...

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Bibliographic Details
Main Authors: Kosuke Tanegashima, Shiki Okamoto, Yuki Nakayama, Choji Taya, Hiroshi Shitara, Rie Ishii, Hiromichi Yonekawa, Yasuhiko Minokoshi, Takahiko Hara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2859050?pdf=render

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http://europepmc.org/articles/PMC2859050?pdf=render

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