Using picoliter droplet deposition to track clonal competition in adherent and organoid cancer cell cultures

Using picoliter droplet deposition to track clonal competition in adherent and organoid cancer cell cultures

Abstract Clonal growth and competition underlie processes of key relevance in etiology, progression and therapy response across all cancers. Here, we demonstrate a novel experimental approach, based on multi-color, fluorescent tagging of cell nuclei, in combination with picoliter droplet deposition,...

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Bibliographic Details
Main Authors: Selami Baglamis, Vivek M. Sheraton, Debora Meijer, Haibin Qian, Ron A. Hoebe, Kristiaan J Lenos, Max A. Betjes, Sander Tans, Jeroen van Zon, Louis Vermeulen, Przemek M. Krawczyk
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42849-w

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https://doi.org/10.1038/s41598-023-42849-w

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